Email this article PENGARUH JUS JAMBU BIJI MERAH (Psidium guajava Linn) TERHADAP KADAR GLUKOSA DARAH
Abstract
Diabetes melitus tipe 2 adalah jenis yang paling banyak terjadi dan selalu meningkat setiap tahunnya. Penatalaksanaan secara non farmakologi dapat memperbaiki kualitas hidup dan mengurangi risiko komplikasi salah satunya dengan jus jambu biji merah. Pada 100 gram jambu biji merah terkandung 87 mg vitamin C, 80,38 mg flavonoid, dan 5,2 gram serat. Kandungan antioksidan tersebut dapat menangkal radikal bebas, anti-diabetes dan anti-inflamasi. Tujuan penelitian untuk mengetahui pengaruh pemberian jus jambu biji merah terhadap kadar glukosa darah puasa pada penderita diabetes melitus tipe 2. Penelitian dilakukan di wilayah kerja Puskesmas Kartasura dengan rancangan penelitian one group pretest postest design terhadap 15 sampel. Jenis glukosa darah yang diuji adalah glukosa darah puasa 10 jam dengan metode GOP-PAP. Intervensi diberikan jus jambu biji merah sebanyak 300 mL/hari selama 12 hari. Analisis statistik menggunakan uji Wilcoxon. Rata-rata nilai glukosa darah puasa pretest 178,67 mg/dL dan postest 168 mg/dL. Hasil uji statistik terdapat pengaruh pemberian jus jambu biji merah terhadap kadar glukosa darah puasa dengan nilai P= 0,030 (<0,05). Disarankan untuk peneliti selanjutnya dapat mengendalikan faktor lain yang dapat meningkatkan resiko diabates melitus.
Type 2 diabetes mellitus is the most common type and always increases every year. Non-pharmacological management can improve quality of life and reduce the risk of complications, one of which is with red guava juice. In 100 grams of red guava contained 87 mg of vitamin C, 80.38 mg of flavonoids, and 5.2 grams of fiber. The content of these antioxidants can ward off free radicals, anti-diabetic and anti-inflammatory. The purpose of the study was to determine the effect of giving red guava juice on fasting blood glucose levels in patients with type 2 diabetes mellitus. The study was conducted in the working area of the Kartasura Health Center with a research design of one group pretest postest design on 15 samples. The type of blood glucose tested was 10-hour fasting blood glucose by the GOP-PAP method. The intervention was given red guava juice as much as 300 mL/day for 12 days. Statistical analysis using the Wilcoxon test. The average fasting blood glucose value of pretest 178.67 mg/dL and postest 168 mg/dL. The results of statistical tests showed the effect of giving red guava juice on fasting blood glucose levels with a value of P = 0.030 (<0.05). It is recommended that researchers can further control other factors that can increase the risk of diabetes mellitus.
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Arieandini, A. (2018). Pengaruh Pemberian Jus Buah Jambu Biji Merah (Psidium guajava) Terhadap Kadar Glukosa Darah Pada Tikus Putih (Rattus norvegicus) Bunting Yang Terpapar Asap Rokok. Universitas Brawijaya.
Cahyana, Y., & Adiyanti, T. (2021). Review: Flavonoids as antidiabetic agents. Indonesian Journal of Chemistry, 21(2), 512–526. https://doi.org/10.22146/ijc.58439
Dafriani, P., Gusti, F. R., & Mardani, A. (2018). Pengaruh Bubuk Kulit Manis (cinnamomun burmani) Terhadap Kadar Glukosa Darah Pasien Diabetes Melitus. Jurnal Kesehatan Medika Saintika, 9(2), 48–56.
Desty Elvira P. (2015). Miracle Juices Penumpas Diabetes dan Hipertensi. Gramedia.
Dinas Kesehatan Kabupaten Sukoharjo. (2021). Profil Kesehatan Kabupaten Sukoharjo.
Eny, M. (2018). Hubungan Umur Dan Status Gizi Dengan Kadar Gula Darah Penderita Diabetes Melitus Tipe II. Jurnal Ilmu Kesehatan, 6(2), 153–163. https://doi.org/https://doi.org/10.32831/jik.v6i2.172
Febrianti, N., Rohmana, I. M., Yunianto, I., & Dhaniaputri, R. (2016). Perbandingan Aktivitas Antiokidan Buah Pepaya (Carica papaya L.) dan Buah Jambu Biji Merah (Psidium guajava L.). Prosiding Seminar Nasional II 2016, Kerjasama Prodi Pendidikan Biologi FKIP Dengan Pusat Studi Lingkungan Dan Kependudukan (PSLK) Universitas Muhammadiya Malang, 1, 1019–1028.
Fitria, N., Andela, M., & Syaputri, Y. Z. (2022). Analisis Efektivitas Biaya Penggunaan Metformin- Glimepirid Terhadap Penurunan Kadar Gula Darah Puasa Pada Pasien Diabetes Mellitus Tipe 2 di Rumah Sakit Universitas Andalas. Jurnal Sains Farmasi & Klinis, 9, 202–207. https://doi.org/10.25077/jsfk.9.sup.202-207.2022
Fitriani, N., Andilala, & Azwar, S. A. (2021). Faktor Risiko Kejadian Diabetes Mellitus. Jurnal Ilmu Kesehatan, 9(2), 94–102. https://doi.org/https://doi.org/10.32831/jik.v9i2.304
Gunawan, S., & Rahmawati, R. (2021). Hubungan Usia, Jenis Kelamin dan Hipertensi dengan Kejadian Diabetes Mellitus Tipe 2 di Puskesmas Tugu Kecamatan Cimanggis Kota Depok Tahun 2019. ARKESMAS (Arsip Kesehatan Masyarakat), 6(1), 15–22. https://doi.org/10.22236/arkesmas.v6i1.5829
Hanhineva, K., Törrönen, R., Bondia-Pons, I., Pekkinen, J., Kolehmainen, M., Mykkänen, H., & Poutanen, K. (2010). Impact of dietary polyphenols on carbohydrate metabolism. International Journal of Molecular Sciences, 11(4), 1365–1402. https://doi.org/10.3390/ijms11041365
Harsari, R. H., Fatmaningrum, W., & Prayitno, J. H. (2018). Hubungan Status Gizi dan Kadar Glukosa Darah pada Pasien Diabetes Melitus Tipe 2 Association between Nutritional Status and Blood Glucose Level in Type 2 Diabetes Mellitus. Journal Kedokteran Indonesia, 6(2), 105–109. https://doi.org/10.23886/ejki.6.8784
Hasneli, Safyanti, & Mardhiyah, A. (2019). The Effectivity of Tomato and Guava Combination Juice and Guava Juice Administration on Blood Glucose Level in Patients with Type II Diabetes Mellitus. KnE Life Sciences, 2019, 74–81. https://doi.org/10.18502/kls.v4i15.5739
Hoerudin. (2012). Indeks Glikemik Buah dan Implikasinya dalam Pengendalian Kadar Glukosa Darah. Buletin Teknologi Pascapanen Pertanian, 8(2), 81–92.
Huang, C. S., Yin, M. C., & Chiu, L. C. (2011). Antihyperglycemic and antioxidative potential of Psidium guajava fruit in streptozotocin-induced diabetic rats. Food and Chemical Toxicology, 49(9), 2189–2195. https://doi.org/10.1016/j.fct.2011.05.032
Indrajat, S., Setiowati, E. R., & S, S. (2019). Pengaruh Konsumsi Suplemen Vitamin C Terhadap Kadar Glukosa Darah Pada Mahasiswa Fakultas Kedokteran Universitas Islam Al - Azhar Tahun 2018. Jurnal Kedokteran, 5(1), 95. https://doi.org/10.36679/kedokteran.v5i1.132
Internasional Diabetes Federation (IDF). (2021). IDF Atlas 10th edition. https://diabetesatlas.org/data/en/world/
Irwan, Fitriyanti, A., & Sirajuddien, B. (2021). Hubungan Riwayat Keluarga Dan Perilaku Sedentari Terhadap Kejadian Diabetes Melitus. Jambura Journal, 3(1), 103–114. https://doi.org/https://doi.org/10.35971/jjhsr.v3i1.7075
Ismawanti, Z., Suparyatmo, J. B., & Wiboworini, B. (2020). The comparative effect of red guava (Psidium guajava. L.) with papaya (Carica papaya) on blood glucose level of type 2-diabetic patients. Romanian Journal of Diabetes, Nutrition and Metabolic Diseases, 27(3), 209–213. https://doi.org/10.46389/rjd-2020-1032
Izzati, A. I., Jaelani, M., Setiadi, Y., Rahmawati, E., & Yulianto. (2021). Pengaruh Jus Tomat Dan Jambu Biji Merah Terhadap Kadar Glukosa Darah Pada Wanita Yang Kelebihan Berat Badan. Jurnal Gizi Indonesia, 9(2), 80–85. https://pdfs.semanticscholar.org/56f4/ac080e6b8e44cdb4080abaa1d5be8d973bbf.pdf
Jasmani, Wirjatdmadi, B., & Adriani, M. (2016). Effect Red Guava Juice (Psidium guajava L) on Blood Glucose Levels Fasting Wistar Rats Induced Pre-diabetes Dexamethasone. International Journal of Preventive and Public Health Sciences, 2(4), 28–31. https://doi.org/10.17354/ijpphs/2016/43
Jiao, Y., Zhang, M., Wang, S., & Yan, C. (2017). Consumption of guava may have beneficial effects in type 2 diabetes: A bioactive perspective. International Journal of Biological Macromolecules, 101, 543–552. https://doi.org/10.1016/j.ijbiomac.2017.03.130
Juwita, E., Susilowati, S., Mauliku, N. E., & Nugrahaeni, D. K. (2020). Faktor Yang Berhubungan Dengan Kadar Gula Darah Pada Penderita Diabetes Melitus Tipe 2 Di Prolanis Puskesmas Kecamatan Cimahi Tengah. Journal of Nutrition College, 9(2), 87–93. https://doi.org/10.14710/jnc.v9i2.26119
Kemenkes RI. (2013). Angka Kecukupan Gizi 2013. Kementerian Kesehatan RI, 53(9), 1689–1699.
Kementrian Kesehatan Republik Indonesia. (2018). Rikesdas. In Badan Penelitian dan Pengembangan Kesehatan (p. 674). http://labdata.litbang.kemkes.go.id/images/download/laporan/RKD/2018/Laporan_Nasional_RKD2018_FINAL.pdf
Kementrian Kesehatan Republik Indonesia. (2019). Peraturan Menteri Kesehatan Republik Indonesia Nomor 28 Tahun 2019 (Angka Kecukupan Gizi Yang Dianjurkan untuk Masyarakat Indonesia). In Menteri Kesehatan Republik Indonesia.
Kent, K., Charlton, K. E., Lee, S., Mond, J., Russell, J., Mitchell, P., & Flood, V. M. (2018). Dietary flavonoid intake in older adults : how many days of dietary assessment are required and what is the impact of seasonality ? Nutrition Journal, 17(7), 1–9. https://doi.org/10.1186/s12937-017-0309-7
Komariah, & Rahayu, S. (2020). Hubungan Usia, Jenis Kelamin Dan Indeks Massa Tubuh Dengan Kadar Gula Darah Puasa Pada Pasien Diabetes Melitus Tipe 2 Di Klinik Pratama Rawat Jalan Proklamasi, Depok, Jawa Barat. Jurnal Kesehatan Kusuma Husada, 11(1), 41–50. https://doi.org/https://doi.org/10.34035/jk.v11i1.412
Krisnatuti, D., Yenrina, R., & Rasjmida, D. (2014). Diet Sehat Untuk Penderita Diabetes Melitus. ANDI.
Kumar, M., Tomar, M., Amarowicz, R., Saurabh, V., Nair, M. S., Maheshwari, C., Sasi, M., Prajapati, U., Hasan, M., Singh, S., Changan, S., Prajapat, R. K., Berwal, M. K., & Satankar, V. (2021). Guava (Psidium guajava L.) Leaves: Nutritional Composition, Phytochemical Profile, and Health-Promoting Bioactivities. MDPI Food Journal, 10(752), 1–20. https://doi.org/10.3390/foods10040752
Latifah, N., & Nugroho, P. S. (2020). Hubungan Stres Dan Merokok Dengan Kejadian Diabetes Melitus Di Wilayah Kerja Puskesmas Palaran Kota Samarinda Tahun 2019. Borneo Student Research, 1(2), 1243–1248.
Li, P. Y., Hsu, C. C., Yin, M. C., Kuo, Y. H., Tang, F. Y., Chao, C. Y., & McPhee, D. J. (2015). Protective effects of red guava on inflammation and oxidative stress in streptozotocin-induced diabetic mice. Molecules, 20(12), 22341–22350. https://doi.org/10.3390/molecules201219831
Lin, C., Kuo, Y., Chen, T., & Chien, C. (2016). Quercetin-Rich Guava (Psidium guajava) Juice in Combination with Trehalose Reduces Autophagy, Apoptosis and Pyroptosis Formation in the Kidney and Pancreas of Type II Diabetic Rats. MDPI Journal Molecules, 21(334), 1–18. https://doi.org/10.3390/molecules21030334
Lin, C. Y., & Yin, M. C. (2012). Renal Protective Effects of Extracts from Guava Fruit (Psidium guajava L.) in Diabetic Mice. Plant Foods for Human Nutrition, 67(3), 303–308. https://doi.org/10.1007/s11130-012-0294-0
Novrian, F., & Hajar, S. (2020). Perbandingan Peningkatan Kadar Glukosa Darah Puasa Sebelum Dan Sesudah Pemberian Madu. Jurnal Ilmiah Simantek, 4(4), 146–152.
PERKENI. (2021). Pedoman Pengelolaan dan Pencegahan Diabetes Melitus Tipe 2 Dewasa di Indonesia 2021. Perkumpulan Endokrinologi Indonesia, 1–117.
Persatuan Ahli Gizi dan Asosiasi Dietisien. (2019). Penuntun Diet dan Terapi Gizi (4th ed.). Penerbit Buku Kedokteran EGC.
Prawitasari, D. S. (2019). Diabetes Melitus dan Antioksidan. KELUWIH: Jurnal Kesehatan Dan Kedokteran, 1(1), 47–51. https://doi.org/https://doi.org/10.24123/kesdok.v1i1.2496
Purwaningtyastuti, R., Nurwanti, E., & Huda, N. (2018). Asupan vitamin C berhubungan dengan kadar glukosa darah pada pasien rawat jalan DM tipe 2. Jurnal Gizi Dan Dietetik Indonesia (Indonesian Journal of Nutrition and Dietetics), 5(1), 44. https://doi.org/10.21927/ijnd.2017.5(1).44-49
Safitri, A., Jahari, A. B., & Ernawati, F. (2017). Konsumsi Makanan Penduduk Indonesia Ditinjau Dari Norma Gizi Seimbang (Food Consumption in Term of the Norm of Balanced Nutrition). Penelitian Gizi Dan Makanan (The Journal of Nutrition and Food Research), 39(2), 87–94. https://doi.org/10.22435/pgm.v39i2.6971.87-94
Sari, P. R. (2020). Hubungan Asupan Karbohidrat, Serat, dan Vitamin D dengan Kadar Glukosa Darah Pada Lansia Di Wilayah Kerja Puskesmas Sukamerindu Kota Bengkulu Tahun 2020. Poltekkes Kemenkes Bengkulu.
Sousa, B. A., & Correia, R. T. P. (2012). Phenolic content, antioxidant activity and antiamylolytic activity of extracts obtained from bioprocessed pineapple and guava wastes. Brazilian Journal of Chemical Engineering, 29(1), 25–30. https://doi.org/10.1590/S0104-66322012000100003
Sun, L., Warren, F. J., & Gidley, M. J. (2019). Natural products for glycaemic control: Polyphenols as inhibitors of alpha - amylase. Trends in Food Science & Technology, 91(2019), 262–273. https://doi.org/10.1016/j.tifs.2019.07.009
Suwinawati, E., Ardiani, H., & Ratnawati, R. (2020). Hubungan Obesitas Dengan Kejadian Diabetes Melitus Tipe 2 Di Posbindu PTM Puskesmas Kendal Kabupaten Ngawi. Journal of Health Science and Prevention, 4(2), 79–84. https://doi.org/10.29080/jhsp.v4i2.388
Takahama, U., & Hirota, S. (2017). Interactions of Flavonoids with α-amylase and starch slowing down its digestion. Food & Function, 1(1), 1–10. https://doi.org/10.1039/C7FO01539A
Tarihoran, Y., & Silaban, D. F. (2022). Hubungan Pola Makan Dengan Kejadian Diabetes Mellitus Di Puskesmas Namorambe Kabupaten Deli Serdang. Jurnal Penelitian Keperawatan Medik, 4(2), 36–42. https://doi.org/10.36656/jpkm.v4i2.883
Utami, B. S., Bintanah, S., & Isworo, J. T. (2015). Hubungan Konsumsi Bahan Makanan Sumber Vitamin C dan Vitamin E dengan Kadar Gula Darah Penderita Diabetes Mellitus Tipe 2 Rawat Jalan di Rumah Sakit Tugurejo Semarang. Jurnal Gizi, 4(1), 18–23.
Widyastuti, N. (2016). Pengaruh Pemberian Jus Jambu Biji Merah (Psidium Guajava L.) Terhadap Kadar Glukosa Darah Pada Atlet Sepakbola Usia 16-18 Tahun by Nurmasari Widyastuti. Journal of Nutrition College, 5(4), 484–490.
World Health Organization (WHO). (n.d.). Diabetes. Retrieved April 21, 2022, from https://www.who.int/health-topics/diabetes#tab=tab_1
DOI: https://doi.org/10.30602/pnj.v6i2.1202
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