C-Reactive Protein Levels among Obese Students at John Paul II Health Academy Pekanbaru: A Cross-Sectional Study

AISYARA YULIANDARI, Irma Br Simanjuntak, Siska Zafrida, Hartini H, Fauzan Fauzan

Abstract


Obesity is associated with chronic low-grade inflammation characterized by increased secretion of pro-inflammatory cytokines from adipose tissue, which may stimulate hepatic synthesis of C-Reactive Protein (CRP). Elevated CRP levels are widely recognized as biomarkers of systemic inflammation and may indicate increased risk for metabolic and cardiovascular disorders. This study aimed to evaluate CRP levels among obese students at Akademi Kesehatan John Paul II Pekanbaru. This study employed a descriptive cross-sectional design involving obese students with Body Mass Index (BMI) ≥27 kg/m² selected using purposive sampling. Serum samples were collected and analyzed for CRP levels using qualitative latex agglutination and semi-quantitative methods. A total of 19 serum samples met the inclusion criteria and were included in the analysis. The results showed that 12 respondents (63.2%) had normal CRP levels (<6 mg/L), while 7 respondents (36.8%) demonstrated elevated CRP levels. Among the positive samples, 5 respondents had CRP levels of 12 mg/L and 2 respondents had CRP levels of 24 mg/L. These findings indicate that obesity does not always correlate with elevated CRP levels, suggesting that additional factors such as dietary habits, physical activity, and lifestyle may influence systemic inflammatory status in obese individuals. Continuous monitoring of inflammatory biomarkers and lifestyle modification remain important in preventing obesity-related complications.

Keywords


C-Reactive Protein, Obesity, Inflammation, Students, Body Mass Index

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References


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DOI: https://doi.org/10.30602/jlk.v9i2.2265

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