THE IMPACT OF GARLIC OIL SUPPLEMENTATION ON HDL AND TRIGLYCERIDE LEVELS IN PATIENTS WITH DYSLIPIDAEMIA: RANDOMIZED CONTROLLED TRIAL

Dhanang Prawira Nugraha; Eki Wulan Oktafiana; Almana Rizka Alifia; Ana Amalia; Arif Santoso

doi:10.30602/jvk.v12i1.1853

THE IMPACT OF GARLIC OIL SUPPLEMENTATION ON HDL AND TRIGLYCERIDE LEVELS IN PATIENTS WITH DYSLIPIDAEMIA: RANDOMIZED CONTROLLED TRIAL

Dhanang Prawira Nugraha, Eki Wulan Oktafiana, Almana Rizka Alifia, Ana Amalia, Arif Santoso

Abstract

Dyslipidaemia is a lipid metabolism disorder that may be characterised by an increase in total cholesterol, LDL, triglycerides, and a decrease in HDL. Complementary therapy that can be used to increase HDL and decrease triglycerides level is garlic oil. Aim of this study is to gain insight potency of garlic oil as complementary therapy in dyslipidaemia. 40 participant were divided into two groups: a control group and a treatment group. The treatment group was administered two 500 mg garlic oil capsules per day, along with 10 mg of simvastatin, while the control group was given 10 mg of simvastatin. We would like to respectfully propose that HDL cholesterol levels be measured after therapy at week 7. the difference in HDL levels between the treatment and control groups was 1.3 mg/dl. while the difference in TG levels between the treatment and control groups was -9.5 mg/dl. Result indicated that garlic oil as supplementary therapy can increase HDL level with p-value < 0,05. However TG level don’t decrease significantly with p-value > 0,05.

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DOI: https://doi.org/10.30602/jvk.v12i1.1853